ARNold, finding terminators (principles, help)

Easy identification of Rho–independent transcription terminators

Insert sequence data

Select options

Search strand:

Color terminator stem and loop:

Inverse U and T – select whether or not you want to keep Us (or Ts) as in input sequence or change them to Ts (or Us):


ARNold finds rho-independent terminators in nucleic acid sequences. The search procedure uses two complementary programs, Erpin and RNAmotif.

To provide a uniform scoring scheme for Erpin and RNAmotif hits, we compute the free energy of the predicted terminator stem-loop structure using RNAfold (Hofacker et al. 1994). This free energy value may be used as a confidence value for predicted terminators.

User's Manual

Input sequences to be analyzed in the text area or upload from a local file. DNA or RNA sequences are accepted. Format is Fasta.

Submit request using the ’Run’ button.
Results are displayed in a single page, with the following information given for each predicted terminator: