Le bond après juillet 99 correspond à l'arrivée d'une nouvelle génération de séquenceurs (à capillaire)
Draft (brouillon): Pour atteindre le statut de brouillon, un clone doit avoir été séquencé au moins avec une couverture de 3. Ceci revient généralement à une couverture effective de 96%, avec des gaps de 500bp en moyenne. Au dessous d'une couverture 3, on parle de pré-draft.
Etat de séquençage des différents chromosomes à la sortie de l'article "Consortium". N50 indique la longueur L telle que 50% des nucléotides sont compris dans des contigs de taille L.
Comparaison des génomes Celera et HGS:
Comparison of the CSA and the PFP assembly. (A) All of chromosome 21, (B) all of chromosome 8, and (C) a 1-Mb region of chromosome 8 representing a single Celera scaffold. To generate the figure, Celera fragment sequences were mapped onto each assembly. The PFP assembly is indicated in the upper third of each panel; the Celera assembly is indicated in the lower third. In thecenter of the panel, green lines show Celera sequences that are in the same order and orientation in both assemblies and form the longest consistently ordered run of sequences. Yellow lines indicate sequence blocks that are in the same orientation, but out of order. Red lines indicate sequence blocks that are not in the same orientation. For clarity, in the latter two cases,lines are only drawn between segments of matching sequence that are at least 50kb long. The top and bottom thirds of each panel show the extent of Celera mate-pair violations (red, misoriented; yellow, incorrect distance between the mates) for each assembly grouped by library size. (Mate pairs that are within the correct distance, as expected from the mean library insert size, are omitted from the figure for clarity.) Predicted breakpoints, corresponding to stacks of violated mate pairs of the same type, are shown as blue ticks on each assembly axis. Runs of more than 10,000 Ns are shown as cyan bars.